Adding a queue name for the MQOutput node with the Destination Mode property set to Destination List
SET OutputLocalEnvironment.Destination.MQ.DestinationData[1].queueName = newQueue;
Changing the default URL for a SOAPRequest node or a SOAPAsyncRequest node request
SET OutputLocalEnvironment.Destination.SOAP.Request.Transport.HTTP.WebServiceURL = newUrl;
Changing the default URL for an HTTPRequest node request
SET OutputLocalEnvironment.Destination.HTTP.RequestURL = newUrl;
Adding a label for the RouteToLabel node
SET OutputLocalEnvironment.Destination.RouterList.DestinationData."label" = newLabel;
N.B. newUrl can be a user defined property.
Extract from IBM Information Center